Association of Iron Deficiency Anemia and Febrile Seizure in Asia: A Systematic Review and Meta-Analysis

Authors

  • Ali Khorshidi Department of Epidemiology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
  • Ali Soleymani Department of Finances, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran
  • Gholamreza Badfar Department of Pediatrics, Behbahan School of Medical Sciences, Behbahan, Iran
  • Parviz Karimi Department of Pediatrics, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
  • zeinab Tardeh Student Research Committee, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
Abstract:

Background: Current findings suggest that iron deficiency anemia (IDA) may be a predisposing factor for febrile seizure (FS), while some studies show the lower prevalence of IDA in the children with FS.The present systematic review and meta-analysis aimed to elucidate the association between IDA and FS. Methods: A comprehensive search was performed using MeSH keywords in databases such as PubMed, Scopus, Embase, ScienceDirect, Web of Science, and Google Scholar without time limit until 2017. Cochrane test and I2 index were used for the evaluation of heterogeneity among the retrieved studies. Data analysis was performed in Comprehensive Meta-Analysis (CMA) software version 2. Results: In total, 38 studies conducted on 3,738 cases and 3,720 controls were reviewed in this meta-analysis. Considering the significant heterogeneity (I2=87.981; P

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Journal title

volume 9  issue 1

pages  42- 52

publication date 2018-03-01

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